Examination (National Level Entrance Exam)
Quantum theory: principles and techniques; applications to a particle in a
box, harmonic oscillator, rigid rotor and hydrogen atom; valence bond and
molecular orbital theories, Hückel approximation; approximate techniques:
variation and perturbation; symmetry, point groups; rotational, vibrational,
electronic, NMR, and ESR spectroscopy
Kinetic theory of gases; First law of thermodynamics, heat, energy, and work;
second law of thermodynamics and entropy; third law and absolute entropy; free
energy; partial molar quantities; ideal and non-ideal solutions; phase
transformation: phase rule and phase diagrams - one, two, and three component
systems; activity, activity coefficient, fugacity, and fugacity coefficient;
chemical equilibrium, response of chemical equilibrium to temperature and
pressure; colligative properties; Debye-Hückel theory; thermodynamics of
electrochemical cells; standard electrode potentials: applications - corrosion
and energy conversion; molecular partition function (translational, rotational,
vibrational, and electronic).
Rates of chemical reactions, temperature dependence of chemical reactions;
elementary, consecutive, and parallel reactions; steady state approximation;
theories of reaction rates - collision and transition state theory, relaxation
kinetics, kinetics of photochemical reactions and free radical polymerization,
homogeneous catalysis, adsorption isotherms and heterogeneous catalysis.
group elements: General characteristics, allotropes, structure and reactions
of simple and industrially important compounds: boranes, carboranes, silicones,
silicates, boron nitride, borazines and phosphazenes. Hydrides, oxides and
oxoacids of pnictogens (N, P), chalcogens (S, Se & Te) and halogens, xenon
compounds, pseudo halogens and interhalogen compounds. Shapes of molecules and
hard- soft acid base concept. Structure and Bonding (VBT) of B, Al, Si, N, P, S,
Cl compounds. Allotropes of carbon: graphite, diamond, C60. Synthesis and
reactivity of inorganic polymers of Si and P.
Elements: General characteristics of d and f block elements; coordination
chemistry: structure and isomerism, stability, theories of metal- ligand bonding
(CFT and LFT), mechanisms of substitution and electron transfer reactions of
coordination complexes. Electronic spectra and magnetic properties of transition
metal complexes, lanthanides and actinides. Metal carbonyls, metal- metal bonds
and metal atom clusters, metallocenes; transition metal complexes with bonds to
hydrogen, alkyls, alkenes and arenes; metal carbenes; use of organometallic
compounds as catalysts in organic synthesis. Bioinorganic chemistry of Na, K.
Mg, Ca, Fe, Co, Zn, Cu and Mo.
Crystal systems and lattices, miller planes, crystal packing, crystal defects;
Bragg's Law, ionic crystals, band theory, metals and semiconductors, Different
structures of AX, AX2, ABX3 compounds, spinels.
methods of analysis: Atomic absorption and emission spectroscopy including
ICP-AES, UV- visible spectrophotometry, NMR, mass, Mossbauer spectroscopy (Fe
and Sn), ESR spectroscopy, chromatography including GC and HPLC and
electro-analytical methods (Coulometry, cyclic voltammetry, polarography –
amperometry, and ion selective electrodes).
Chirality of organic molecules with or without chiral centres. Specification of
configuration in compounds having one or more stereogenic centres. Enantiotopic
and diastereotopic atoms, groups and faces. Stereoselective and stereospecific
synthesis. Conformational analysis of acyclic and cyclic compounds. Geometrical
isomerism. Configurational and conformational effects on reactivity and
mechanism: Methods of determining reaction mechanisms. Nucleophilic and
electrophilic substitutions and additions to multiple bonds. Elimination
reactions. Reactive intermediates- carbocations, carbanions, carbenes, nitrenes,
arynes, free radicals. Molecular rearrangements involving electron deficient
synthesis: Synthesis, reactions, mechanisms and selectivity involving the
following- alkenes, alkynes, arenes, alcohols, phenols, aldehydes, ketones,
carboxylic acids and their derivatives, halides, nitro compounds and amines. Use
of compounds of Mg, Li, Cu, B and Si in organic synthesis. Concepts in multistep
synthesis- retrosynthetic analysis, disconnections, synthons, synthetic
equivalents, reactivity umpolung, selectivity, protection and deprotection of
reactions: Electrocyclic, cycloaddition and sigmatropic reactions. Orbital
correlation, FMO and PMO treatments.
Basic principles. Photochemistry of alkenes, carbonyl compounds, and arenes.
Photooxidation and photoreduction. Di-p- methane rearrangement, Barton reaction.
compounds: Structure, preparation, properties and reactions of furan,
pyrrole, thiophene, pyridine, indole and their derivatives.
Structure, properties and reactions of mono- and di-saccharides, physicochemical
properties of amino acids, chemical synthesis of peptides, structural features
of proteins, nucleic acids, steroids, terpenoids, carotenoids, and alkaloids.
Principles and applications of UV-visible, IR, NMR and Mass spectrometry in
the determination of structures of organic molecules.